… ProQR Announces Proposed Underwritten Public Offering of Ordinary Shares … addition, ProQR expects to grant the underwriters a 30-day option to purchase up to an additional 15% of the offering … existing cash and cash equivalents, to advance clinical development of its product candidates, to progress its other …
… oligonucleotide QR-110 for treatment of inherited retinal dystrophy in adults and children with LCA10 Presenter : David … Poster title: Structure-based computational approach for optimizing oligonucleotides for A-to-I editing Poster #: 29 … orphan drug designation in the United States and the European Union and received fast-track designation by the …
… 1b safety, tolerability and exploratory efficacy trial. Top-line data to be reported in mid-2017 Top-line data from a … of QR-010. A full study presentation is planned for the European Cystic Fibrosis Society Conference in June 2017. … QR-010 is designed to be self-administered via an optimized eFlow® Nebulizer (PARI Pharma GmbH). eFlow® is a …
… - Nucleic Acids . LCA10 is a severe inherited retinal dystrophy associated with mutations in the CEP290 gene. … process by which QR-110 was identified as a potentially optimal therapeutic candidate using a patient-derived retinal … suggest the pharmacodynamic, pharmacokinetic and safety properties make QR-110 a promising candidate for the …
… at NACFC on October 27 Noreen Henig, M.D., Chief Development Officer of ProQR and John P. Clancy, M.D., … QR-010 is designed to be self-administered via an optimized eFlow ® Nebulizer (PARI Pharma GmbH). eFlow ® is a … orphan drug designation in the United States and the European Union. The QR-010 project has received funding from …
LEIDEN, Netherlands & CAMBRIDGE, Mass., June 18, 2024 (GLOBE NEWSWIRE) -- ProQR Therapeutics NV (Nasdaq: PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies, today announced it will participate in the RNA Editing Summit, June 18-20, 2024, in Boston, Mas
… Team. During the event, the Company will showcase its proprietary Axiomer ® RNA-editing technology platform, announce initial pipeline targets for internal development, and provide guidance on the advancement of … has led in the development of structure-guided methods for optimizing chemically modified oligonucleotides for …
… “QR-1123 aims to block expression of the toxic mutated rhodopsin protein in the retina thereby targeting the … RHO ) gene. The trial will include single-dose escalation (open label) groups and multiple-dose escalation … function and retinal structure will be assessed through ophthalmic endpoints such as visual acuity, visual field and …
… Board. Dr. Dryja will play a key strategic role in the development and advancement of ProQR’s growing ophthalmology pipeline. LEIDEN, The Netherlands, Nov. 09, …
… (FDA) for its molecule QR-010 that is in clinical development for the treatment of patients with CF due to the … CFTR function, the nasal potential difference (NPD). This open label 28-day study enrolls 16 CF patients, 8 homozygous (carrying two copies) for the ΔF508 mutation and 8 compound heterozygous …