Applicability of a structure-based modelling approach as a tool for in silico screening of oligonucleotides for targeted RNA editing presented at Oligonucleotide Therapeutics Society (OTS) 2018 by Julien Boudet
… cellular systems. Proficiency in Cell-type specific method development: Proven ability to develop and optimize methods using endosomal escape reagents (strongly …
… simulations to support go/no-go decisions, trial design optimization, and regulatory interactions. Skills and … are a true believer of the value of a workforce in which people from diverse backgrounds are encouraged to develop themselves, personally and professionally. We believe …
… and Cambridge, Massachusetts, USA. ProQR is focused on the development of life changing RNA therapies to meet the unmet … activities include: Prepare mechanistic minimal PBPK and/ (population) PKPD M&S-based strategies to support discovery … generate predictive (human) exposure profiles and to guide optimal dosing strategies and ensure therapeutic efficacy and …
… approaches to drive scientific and operational excellence. Develop and determine optimal methods for new assignments by … we are true believers of the value of a workforce in which people from diverse backgrounds are encouraged to develop … and professionally. We believe that happy and energized people, working well together in an environment in which they …
This presentation highlights the therapeutic possibilities of Axiomer platform that are not limited to disease causing mutations and can potentially address high unmet medical needs by editing wild-type RNA to engineer proteins or modify their function as well as creating de novo mutations.
… presentations by ProQR Management on the company's proprietary Axiomer® RNA editing technology platform, … editing in humans. In addition, his group has led in the development of structure-guided methods for optimizing chemically modified oligonucleotides for …
… are a true believer of the value of a workforce in which people from diverse backgrounds are encouraged to develop themselves, personally and professionally. We believe that happy and energized people, working well together in an environment in which they …
