… Structure-based computational approach for optimizing oligonucleotides for A-to-I editing Applicability … J Boudet et al. A robust computational approach is developed to screen for compatible interactions between …
… simulations to support go/no-go decisions, trial design optimization, and regulatory interactions. Skills and … are a true believer of the value of a workforce in which people from diverse backgrounds are encouraged to develop themselves, personally and professionally. We believe …
… data into standardized, AI-ready datasets Automate and optimize data flows to reduce manual steps and improve … using scripting and containerized tools (e.g., Docker) Develop, train, and evaluate AI models using JAX or PyTorch … initiatives, including FAIR-compliant schema development, metadata standards, and integration with …
… and Cambridge, Massachusetts, USA. ProQR is focused on the development of life changing RNA therapies to meet the unmet … activities include: Prepare mechanistic minimal PBPK and/ (population) PKPD M&S-based strategies to support discovery … generate predictive (human) exposure profiles and to guide optimal dosing strategies and ensure therapeutic efficacy and …
… approaches to drive scientific and operational excellence. Develop and determine optimal methods for new assignments by … we are true believers of the value of a workforce in which people from diverse backgrounds are encouraged to develop … and professionally. We believe that happy and energized people, working well together in an environment in which they …
This presentation highlights the therapeutic possibilities of Axiomer platform that are not limited to disease causing mutations and can potentially address high unmet medical needs by editing wild-type RNA to engineer proteins or modify their function as well as creating de novo mutations.
… presentations by ProQR Management on the company's proprietary Axiomer® RNA editing technology platform, … editing in humans. In addition, his group has led in the development of structure-guided methods for optimizing chemically modified oligonucleotides for …
… are a true believer of the value of a workforce in which people from diverse backgrounds are encouraged to develop themselves, personally and professionally. We believe that happy and energized people, working well together in an environment in which they …
